Doctoral Schools WUT

The area of scientific research concerns the determination and correlation of the basic thermodynamic and physicochemical properties of a new class of pure organic salts and their binary systems with aliphatic and aromatic hydrocarbons and with water. The conducted research is aimed at determining … More

• Promoter Ph.D., D.Sc. Marta Królikowska
• Keywords: Ciecze jonowe | Korelacja | Węglowodory | Właściwości termodynamiczne |

The main research interests are focused on the design and fabrication of bioanalytical microsystems (Lab-on-a-Chip flow-through microsystems). These microsystems are intended for the development of new analytical and bioanalytical procedures such as: conducting analytical reactions at the microscal… More

• Promoter prof. Michał Ludwik Chudy
• Keywords: Cytotoksyczność | Lab-on-Chip | Nanomateriały | Terapie przeciwnowotworowe |

Searching for antiviral drugs - identification of new indications for drugs (drug repurposing) against COVID 19. Studies on the mast cell activation syndrome (MC) and the role of MC in the inflammatory process responsible for the severe course of COVID-19 will help identify new targets for anti-COV… More

• Promoter Phd Monika Maria Staniszewska
• Keywords: Burza cytokin | COVID-19 | Leki przeciw-wirusowe | Mastocyty |

Understanding the action mode of oncolytic therapy, tumor biology, and specific studies of the immune response. Development of new and more effective methods of cancer treatment (e.g. pleural mesothelioma) using an oncolytic virus encoding ICOS ligand in combination with an anti-PD-1 checkpoint inh… More

• Promoter Phd Monika Maria Staniszewska
• Keywords: Adenowirusy | Immunoterapia | Terapia onkolityczna |

Studies on the calcineurin signaling pathway in the innate immune response over pathogenic fungal infections. Regulatory interaction analyzes of the Candida calcineurin subunit Cal albicans (coded by the CNB1 gene) with mast cells (mast cells) – sensors congenital and acquired immunity effectors. D… More

• Promoter Phd Monika Maria Staniszewska
• Keywords: Inhibitory kalcyneuryny | Kandydozy | Wrodzona odpowiedź immunologiczna |

Spectroscopic ""fingerprints"" of cells – acquisition and numerical analysis. Thanks to their uniqueness, fingerprints are one of the basic biometric features used to identify people. Identification techniques in chemistry can also rely on the recognition of ""patterns"" - that is, signal pattern… More

• Promoter prof. Patrycja Elżbieta Ciosek-Skibińska
• Keywords: Bioanalityka | Fingerprinting | Fluorescencja dwuwymiarowa | Komórki |

""Fingerprints"" of quantum dots for analytical and bioanalytical purposes. The subject of the PhD thesis is related to the use of nanomaterials - quantum dots - to create fluorescent ""fingerprints"" for the identification / determination of selected bioanalytes with a similar structure: amino a… More

• Promoter prof. Patrycja Elżbieta Ciosek-Skibińska
• Keywords: Bioanalityka | Fluorescencja | Kropki kwantowe | Nanontechnologia |

Ion-sensitive nano- and microspheres - fabrication, characterization and testing of sensory properties. In recent years, nanotechnology has developed a number of tools enabling the fabrication, characterization, and study of the potential applications of a number of nanomaterials, which we use mo… More

• Promoter prof. Patrycja Elżbieta Ciosek-Skibińska
• Keywords: Bioanalityka | Chemosensory | Nanomateriały | Nanontechnologia |

Electronic tongue - study of the correlation of (soft) sensor signals with organoleptic properties. The ""Holy Grail"" of the pharmaceutical and food industry is the replacement of trained organoleptic evaluation experts (human panel) with machine-based taste and smell systems, so-called taste a… More

• Promoter prof. Patrycja Elżbieta Ciosek-Skibińska
• Keywords: Elektroniczny język | Sensor smaku | Uczenie maszynowe | Właściwości organoleptyczne |

The research topic involves design of luminescent compounds with a special emphasis on systems that exhibit Thermally Activated Delayed Fluorescence (TADF). The research will mainly devoted to using novel heterocyclic organoboron cores, featuring strongly electron-acceptor properties, as key build… More

• Promoter prof. Sergiusz Mariusz Luliński
• Keywords: Diody OLED | Fluorescencja | Związki boroorganiczne |

Thermodynamics of solutions, i.e., thermodynamic and physical properties of liquid mixtures. Phase equilibria (vapor-liquid, liquid-liquid, solid-liquid) in binary and multicomponent systems. The excess functions of mixing - Gibbs function, enthalpy and volume. Relationships between the properties … More

• Promoter Ph.D., D.Sc. Tadeusz Edmund Hofman
• Keywords: Funkcje nadmiarowe | Metody udziałów grupowych | Równowagi fazowe | Termodynamika roztworów |

Melanoma is the skin cancer with the highest mortality and increasing incidence in the world population. Despite many years of efforts, there is no effective therapy for metastasis of this cancer and a lot of research is devoted to searching for new solutions using the modern methods and technologi… More

• Promoter Ph.D., D.Sc. Tomasz Kajetan Kobiela
• Keywords: Analiza bioinformatyczna | Czerniak | Mikrowaga kwarcowa | Terapia skojarzona |

Exosomes are extracellular signaling molecules secreted by eukaryotic cells, the presence of which in body fluids makes them a potential and easily accessible biomarkers of various pathological processes, including cancer. Taking blood serum rich in exosomes from patients with cancer is a simple an… More

• Promoter Ph.D., D.Sc. Tomasz Kajetan Kobiela
• Keywords: Egzosomy | Immunoterapia | Teranostyka | Terapia celowana |

My research group works on new materials for energy storage devices such as batteries and supercapacitors. The recent breakthrough studies of the group has led to the design and development of a novel family of Huckel-type salts for application in electrolytes used in lithium and/or sodium ion bat… More

• Promoter prof. Władysław Grzegorz Wieczorek
• Keywords: Dodatki | Elektrolity | Superkondensatory |

Organometallic chemistry of transition metals and homogeneous catalysis, in particular: synthesis of novel homochiral ligands based on ansa-ferrocenes and their application in asymmetric catalysis olefin metathesis in transition metal coordination spheres catalysed with Grubbs catalysts (I or II … More

• Promoter Ph.D., D.Sc. Włodzimierz Krzysztof Buchowicz
• Keywords: Karbeny N-heterocykliczne | Kataliza homogeniczna | Metaloceny | Metateza olefin |

Electrochemical sensors based on novel molecular receptors Chemical sensors are attractive analytical devices, which can deliver real-time and on-line information on the presence of specific compounds in complex samples. Due to their high selectivity, sensitivity and wide spectrum of design soluti… More

• Promoter prof. Wojciech Artur Wróblewski
• Keywords: Elektroanaliza | Projektowanie i synteza receptorów | Receptory molekularne | Sensory elektrochemiczne |

Modern multi-sensor systems (electronic tongue) for the analysis of pharmaceuticals Electronic tongue is a modern device that provide automatic analysis and classification (including identification and quality assessment) of complex samples. Specially selected set of cross-sensitive sensors (senso… More

• Promoter prof. Wojciech Artur Wróblewski
• Keywords: Analiza farmaceutyków | Elektroniczny język | Sensory chemiczne | Techniki chemometryczne |

Redox activity of metal-peptide complexes Peptides are essential biomolecules associated with learning and neurodegeneration processes (Aβ peptides), the innate immune response (histatins) and wound healing (a GHK peptide). It should be emphasized that in many cases, the biological activity of suc… More

• Promoter prof. Wojciech Artur Wróblewski
• Keywords: Choroba Alzheimera | Elektrochemia | Leki przeciwdrobnoustrojowe | Metalokompleksy peptydowe |

The current research interests focus on miniaturized analytical systems (Lab-on-a-Chip) for monitoring of bioanalytes. Emphasis is now also being laid on the development of polymeric chips for human cell culture (Cell-on-a-Chip) in unique, in vivo-mimicking microenvironment where studies of cell… More

• Promoter prof. Zbigniew Włodzimierz Brzózka
• Keywords: Cytotoksyczność | Inżynieria komórkowa i tkankowa | Mikrobioanalityka | Mikrosystemy Lab-on-a-Chip |

The topic of work will be the development of a biochemical microsystem for the analysis of a complex profile of hormone secretion (hormonal fingerprints) using various analytical methods. Analysis of the profile of hormones secreted by the pancreas is of great importance in the diagnosis and dev… More

• Promoter prof. Zbigniew Włodzimierz Brzózka
• Keywords: Biochemiczne mikrosystemy | Diagnostyka chorób trzustki | Insulina | Profil hormonów |