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Promotor:
prof. Wojciech Artur Wróblewski
Jednostka:
Faculty of Chemistry
E-mail:
wojciech.wroblewski@pw.edu.pl
Dane kontaktowe:
Gmach Chemii, ul. Noakowskiego 3 (pok. 17), tel. 22 234 56 31
Repozytorium PW:

Wykaz obszarów badawczych:

Obszar badawczy Dziedzina naukowa
Redox activity of metal-peptide complexes Peptides are essential biomolecules associated with learning and neurodegeneration processes (Aβ peptides), the innate immune response (histatins) and wound healing (a GHK peptide). It should be emphasized that in many cases, the biological activity of such peptides is strongly related to their ability to bind transition metal cations and the redox activity of the formed metal complexes. The research aims to characterize the redox properties of the complexes of peptides with transition metal cations in terms of describing their biological activity and role in many biological processes. Moreover, new peptides and peptide metallocomplexes for pharmacological applications, including therapies for Alzheimer's disease and antimicrobial treatments, are designed. Finally, research on the application of peptide-based complexes as molecular receptors of electrochemical sensors suitable for medical and environmental diagnostics is also conducted.
Chemical-Sciences