Wykaz obszarów badawczych związanych z tagiem Nanoczastki:
| # | Obszar badawczy | Dziedzina naukowa |
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| 1 |
Synthesis, studies on properties and application of nanoparticles in the construction of biotests and biosensors - the research will involve synthesizing hybrid nanoparticles with the desired magnetic, optical and catalytic properties, which after surface modification with selected receptors (antibodies, oligonuclotides or others) will be used in the development of modern bioanalytical tools for determination of clinically significant disease biomarkers.
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| 2 |
Synthesis and application of nanoparticles in therapies - as part of the research, nanoparticles with the desired optical, magnetic and catalytic properties, which can be used in anti-cancer therapies through the ability to generate heat under the influence of infrared radiation, the applied magnetic field or the ability to catalytically generate reactive oxygen species and other types of toxic radicals, will be synthesized. The nanoparticles will be modified with receptors / ligands that recognize proteins characteristic for cancer cells.
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| 3 |
- Bioavailability investigation of selected nanoparticles (NPs)
- Investigation of nanoparticles (NPs) metabolism in edible plants
- New extraction methods of nanoparticles from plant tissue and food - ionic liquids, NADES
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| 4 |
The main areas of scientific of prof. Paweł Sobieszuk include chemical engineering and bioprocess engineering. His research works are tackling the problems concerning nanohydroxyapatite synthesis and characterization for application in bone regeneration therapy. Especially important is designing the method of obtaining composites of polymer and nanohydroxyapatite in such a way that the mechanical properties of polymer allow for it to be used in 3D printing while preserving the osteoinductive properties of hydroxyapatite. Because of these two properties, it is possible to use such composites in the 3D printing of osteoinductive implants of bones. His other study area focuses on gas-liquid systems, including nanobubble technology, properties, and application. Nanobubbles are a novel nanomaterial composed of gas spheres in liquid with or without a surfactant shell surrounding the gas. Such objects are used in multiple areas of both industry and medicine. Prof. Sobieszuk particularly finds it interesting to study the effect of gas nanobubbles on living matter, bacteria, microscopic fungi, and animal cells.
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| 5 |
In recent years, an increasing number of various formation methods of metal-based nanometric structures has been notified. These nanomaterials can be applied in many branches of life, including medicine and agriculture. Despite the fast development of the synthetic methods, these dedicated to characterizing the produced chemical structures progressed slower, which induces the acute need for their practical elaboration. As part of the presented research area, a modern analytical platform will be proposed to study selected metal-based nanomaterials (or their connections with drugs) in complex sample matrices using advanced mass spectrometry techniques, including single-particle or single-cell inductively coupled plasma mass spectrometry. Such techniques may enable understanding of many processes that metallic nanomaterials undergo in the environment or living organisms.
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| 6 |
The use of electrospun materials in the construction of modern bioanalytical tools - Electrospinning is a modern technique for producing polymeric mats (both from natural and synthetic polymers) with an expanded surface area and high porosity. The method also makes it possible to produce composite structures enriched with nanoparticles, which boosts their range of applications by giving them new properties. Such mats can be utilized in bulk technologies (catalytic processes or wastewater treatment) or for more sophisticated biomedical or bioanalytical applications. Their numerous unique features also allow their use in the construction of biosensors and biotesters as transducer modifiers, as well as layers in/on which the most important receptors, from the point of view of these bioanalytical devices, are immobilized.
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