Wykaz obszarów badawczych związanych z tagiem Immunoterapia:
| # | Obszar badawczy | Dziedzina naukowa |
|---|---|---|
| 1 |
Exosomes are extracellular signaling molecules secreted by eukaryotic cells, the presence of which in body fluids makes them a potential and easily accessible biomarkers of various pathological processes, including cancer. Taking blood serum rich in exosomes from patients with cancer is a simple and minimally invasive procedure. Methods for detecting exosomes can be used not only to monitor the stage of a given tumor, but also to assess the effectiveness of the applied therapy, including immunotherapy, targeted or combined therapy. The aim of the project is to optimize a specific method of isolation and determination of the content exosomes in blood samples from patients in order to monitor the therapy of cancer.The project is implemented in cooperation with Charité - Universitätsmedizin Berlin as part of the "Institutpartnerschaft" program granted by Alexander von Humboldt foundation.
|
|
| 2 |
Understanding the action mode of oncolytic therapy, tumor biology, and specific studies of the immune response. Development of new and more effective methods of cancer treatment (e.g. pleural mesothelioma) using an oncolytic virus encoding ICOS ligand in combination with an anti-PD-1 checkpoint inhibitor. Research on the use of combined therapy: in vitro, ex vivo, and in vivo with the use of humanized mouse models.
|