Wykaz obszarów badawczych związanych z tagiem Diagnostyka-molekularna:
| # | Obszar badawczy | Dziedzina naukowa |
|---|---|---|
| 1 |
Fast molecular diagnostics based on nucleic acid analysis enables the detection not only diseases caused by mutations in genes or the identification of pathogenic microorganisms but also the selection of an appropriate treatment method for each patient. Its development is related to the latest achievements in the field of microfluidic systems and integrated sensors and biosensors. This combination allows for efficient and fully automatic preparation of biological material samples and their analysis.
At this area research is focused on the development of new electrochemical sensors dedicated to effective and selective detection of selected nucleic acid sequences. In particular, samples derived from isothermal DNA amplification reactions will be considered. The high content of proteins in such samples force the use of new approaches leading to the elimination of their influence on the processes taking place at the electrode/solution interface. In particular, this applies to selected nanomaterials and elements of biosensitive receptor layers that eliminates the possibility of non-specific protein adsorption.
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| 2 |
Obtaining, characterizing and optimizing the production of fusion polymerases enabling the effective implementation of the genetic material amplification reaction directly in clinical samples in a much faster manner than the counterparts available on the market.
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