Wykaz obszarów badawczych związanych z tagiem Systemy-dostarczania-lekow:
| # | Obszar badawczy | Dziedzina naukowa |
|---|---|---|
| 1 |
Research focuses on the development and characterization of advanced biomaterials for implantology, tissue engineering and drug delivery systems.
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| 2 |
Although cisplatin and oxaliplatin are anticancer drugs frequently applied in the chemotherapy of various malignant neoplasms, their non-selective transportation into cells results in serious side effects of treatment. Non-toxic nanomaterials such as liposomes can be used to ensure the drug's targeted delivery. In addition, features such as biocompatibility (similarity to cell membranes), biodegradability, ease of synthesis and surface modification, and the ability to regulate the degree of drug encapsulation distinguish them from other nanomaterials tested as drug nanocarriers. Even though at least a few liposome systems have been approved for the market, none contain platinum drugs. This situation may result in the utilization of ineffective analytical tools for their characterization. As part of the proposed research, methodologies for studying changes in in vitro liposomal systems of targeted cisplatin/oxaliplatin delivery using techniques based on mass spectrometry detection will be developed.
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