Wykaz obszarów badawczych związanych z tagiem Inhibitory-kalcyneuryny:
| # | Obszar badawczy | Dziedzina naukowa |
|---|---|---|
| 1 |
Studies on the calcineurin signaling pathway in the innate immune response over pathogenic fungal infections. Regulatory interaction analyzes of the Candida calcineurin subunit Cal albicans (coded by the CNB1 gene) with mast cells (mast cells) – sensors congenital and acquired immunity effectors. Determining whether deletion or chemical inhibition of calcineurin by a proxifylin derivative (our preliminary studies of in vitro activity and the use of molecular modeling) and other inhibitors induce defense mechanisms at the Cal entry site: immune synaptic organization, phagocytic capacity of mast cells and production of NO, ROS and IL- 10 (key in the antifungal response).
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