Wykaz obszarów badawczych związanych z tagiem Analiza-metabolitów:
| # | Obszar badawczy | Dziedzina naukowa |
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| 1 |
The PhD thesis will focus on developing a research methodology combining Organ-on-Chip technology with high-resolution mass spectrometry to monitor interorgan communication and assess therapy efficacy and safety. The project will develop multi-organ microfluidic systems that replicate the physiological connections between selected tissues, including the liver, and drug target tissues. The use of mass spectrometry will enable the quantitative analysis of metabolites, biomarkers, and drug biotransformation products in real time. The result will be a comprehensive methodology supporting preclinical research, identifying mechanisms of drug action, and predicting their efficacy and systemic toxicity.
Additional information Assistant supervisor: dr inż. Agnieszka Żuchowska.
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