Wykaz obszarów badawczych związanych z tagiem Affinity:
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The evolutionarily directed affinity of nucleic acids and antibodies toward the corresponding analytes (complementary sequences, antigens) makes them applicable, among other things, as receptors for biosensing layers of affinity biosensors. Molecular recognition occurring in several nanometer interfacial space (surface/solution) translates into a very strong response of biological sensors and obtaining low detection limits or very high sensitivity of conducted analyses. Research topics include the design and analysis of receptor layers of affinity biosensors (nucleic acids, including aptamers and antibodies) as well as the design of ready-to-use sensor solutions, including those manufactured using substrates in printed electronics technology. Such solutions, due to a high degree of miniaturization, the ability to simultaneously detection up to a dozen analytes, low cost or freedom in production scalability, have a high degree of application through integration into modern microfluidic devices and ultimately into POC type diagnostic tools.
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