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Promotor:
Ph.D., D.Sc. Magdalena Matczuk
Jednostka:
Faculty of Chemistry
E-mail:
magdalena.matczuk@pw.edu.pl
Dane kontaktowe:
Gmach Chemii, pokoj 318, czwartki 10-12
Repozytorium PW:

Wykaz obszarów badawczych:

Obszar badawczy Dziedzina naukowa

Liposomes are nanosized vesicles built from a phospholipid double layer. Currently, intensive works are carried out on the broad application of this type of nanomaterials in more effective delivery of active compounds, e.g., in dietary supplements. Unfortunately, it is a lack of studies confirming the increased bioavailability of active compounds from liposomal preparations than from classic ones. Therefore, research aimed at understanding their metabolic pathways (and comparing them with supplements in which nanomaterials are not used) in conditions that simulate the human body is a significant issue. As part of the dissertation, the changes mentioned above concerning selected supplements, e.g., zinc or vitamin B12, will be tested using, on the one hand, modern methods of in vitro simulation (enzymatic digestion/degree of absorption into intestinal villus cell lines), and on the other hand, high-sensitive mass spectrometry detection techniques. 

Chemical-Sciences