Wykaz obszarów badawczych:
| Obszar badawczy | Dziedzina naukowa |
Development and application of magnetic nanoparticles in the procedure of photothermal therapy
Photothermal therapy involves the use of local heating of the tissues, resulting in the “relaxation” of the cell membrane and denaturation of the proteins, leading to cell death. In this therapy, photothermal “factors” are used that absorb the radiation of the laser and loose delivered energy by thermal emission. Selected types of nanoparticles can be used as photoactive agents.
The PhD thesis will be aimed at designing nanoparticles with magnetic properties that can be used in photothermal therapy. The use of appropriate modification of the surface of nanoparticles will be aimed at limiting their cytotoxicity, extending their biodistribution or directing their penetration into tumor cells. Properly designed nanoparticles of this type should have unique magnetic and photothermal properties, and at the same time be characterized by good biocompatibility and easy functionalization. It is important that the obtained nanoparticles absorb electromagnetic radiation in the near infrared region, because for wavelengths in this range there is the so-called tissue biological window.
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Chemical-Sciences |
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