Wykaz obszarów badawczych związanych z tagiem Mikrosystem:
| # | Obszar badawczy | Dziedzina naukowa |
|---|---|---|
| 1 |
Development of a lab-on-a-chip system to improve sperm parameters
Infertility is a global health problem that affects a large part of the population. One of its causes is male infertility, which has been increasing for some time. Thanks to assisted reproductive methods, it is possible to solve this problem to some extent. Therefore, there is a need not only to conduct tests that assess the quality of sperm, but also those aimed at selecting normal sperm (then used in the in vitro method).
The aim of the doctorate is to develop a microsystem enabling the selection of appropriately motile sperm with the correct structure. After introducing sperm into the microsystem, it will be possible not only to track their movement, but also to study their response to various types of stimuli (e.g. chemical compounds, temperature). Thanks to the developed lab-on a-chip system, it will be possible to select sperm with the best parameters (due to the possibility of using them in in vitro fertilization) from the analyzed sperm. One of the key features of the developed microsystem will be effective selection, characterized by both high efficiency and selectivity (only clinically useful amount of sperm is obtained). The selected sperm can then be used to fertilize the egg in an in vitro procedure. This would increase the chance of obtaining a healthy (normal) embryo, and thus increase the effectiveness of the in vitro procedure.
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